Phosphate transporter 1

Author: mvos

August undefined, 2024

WebEOS789 is a potent, pan-phosphate transporter inhibitor, inhibits phosphate uptake in a noncompetitive manner for human NaPi-IIb, PiT-1, and PiT-2 with IC50 of 6.8, 1.5 and 1.7 uM, respectively. EOS789 also inhibited phosphate uptake in normal rat intestinal brush border membrane vesicles with IC50 of 3.1 uM, also inhibited human or rat NaPi ... WebWe used a combination of deletion mutagenesis, point mutations and protein chimeras to identify a short motif prior to the first transmembrane domain of the T. gondii apicoplast phosphate transporter 1 (APT1) that is necessary for apicoplast trafficking.

Phosphate Transporter - an overview ScienceDirect Topics

WebFeb 1, 2010 · The Pho84 phosphate transceptor in yeast transports phosphate and mediates rapid phosphate activation of the protein kinase A (PKA) pathway during growth induction. We have now identified several phosphate-containing compounds that act as nontransported signaling agonists of Pho84. WebAug 29, 2024 · Phosphate transporter PHT1;1 is a key determinant of phosphorus acquisition in Arabidopsis natural accessions Authors Pei-Shan Chien 1 , Ya-Ting Chao 1 , … css for safari browser only

Transporters: the molecular drivers of arsenic stress tolerance in ...

WebApr 15, 2016 · PiT-1/SLC20A1 and PiT-2/SLC20A2 are members of the mammalian type-III inorganic phosphate (Pi) transporters encoded by the SLC20 genes. The broad distribution of SLC20A1 and SLC20A2 mRNAs in mammalian tissues is compatible with housekeeping maintenance of intracellular Pi homeostasis by transporting Pi from intrastitial fluid for … WebJan 5, 2024 · PHR1, a key regulator in PSR signaling, and PHF1, which facilitates plasma membrane targeting of Pi transporter, negatively regulate SA-mediated immunity and likely facilitate symbiosis under low P conditions. NLA mediates degradation of Pi transporters at plasma membranes impact on plant immunity through SA and SA downstream signaling. WebPhosphate uptake through Pit-1 is essential for vascular smooth muscle cell calcification and phenotypic modulation in response to elevated phosphate. Two highly conserved glutamate residues critical for sodium-dependent phosphate transport are revealed by uncoupling transport function from retroviral receptor function. earle rayner obituary

Inorganic phosphate transporter family - Wikipedia

Mutation of the chloroplast‐localized phosphate transporter OsPHT2;1 …

WebApr 4, 2024 · Food fortification programs to reduce iron deficiency anemia require bioavailable forms of iron that do not cause adverse organoleptic effects. Rodent studies show that nano-sized ferric phosphate (NP-FePO4) is as bioavailable as ferrous sulfate, but there is controversy over the mechanism of absorption. We undertook in vitro studies to … http://animbiosci.org/upload/pdf/ab-22-0058.pdf css for safariWebMar 31, 2013 · Figure 1: Structure of the high-affinity phosphate transporter, PiPT. The structure represents an inward facing occluded state of the phosphate transporter in … earl erickson obituary

"Web• OsPT2, the most abundantly expressed Pi transporter in the roots, is also significantly up-regulated in ltn1 and dramatically induced by Pi starvation. OsPT2-overexpressing and knockdown plants displayed significantly increased and decreased rates of selenite uptake, respectively, suggesting that OsPT2 plays a crucial role in selenite uptake. " - Phosphate transporter 1

Phosphate transporter 1

WebPhosphate administration through the duodenum results in phosphate uptake in the liver and bone. To analyze phosphate dynamics following intestinal absorption, a sodium phosphate (80 μmol/animal) solution containing 32 P was administered through the duodenum to normal rats (Duo group) (Fig. 1 a). The 32 P level in the inferior vena cava …

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WebThe stoichiometry of protons to phosphate at pH 7.0 was found to be 1.5, close to the anticipated value because phosphate exists in the HPO 4 2− and H 2 PO 4 − forms in … WebFunctionally-characterized members of the family appear to catalyze inorganic phosphate (P i) or inorganic sulfate uptake either by H + or Na + symport. Both PitA ( TC# 2.A.20.1.1) and PitB ( TC# 2.A.20.1.2) of E. coli probably catalyze metal ion·phosphate:H + symport, where Mg 2+, Ca 2+ or Zn 2+ (and probably other divalent cations) can ...

WebFeb 6, 2024 · Phosphate transporters (such as PHT1 family proteins) are critical in fine-tuning Pi homeostasis in plant cells, which affect the sensitivity to As (V) stress ( Li et al. 2016 ). WebNov 9, 2015 · Phosphate is an essential nutrient for plant growth, and inorganic phosphate (Pi) is stored largely in the vacuole of plant cells. Thus, vacuolar Pi maintains homeostasis of cytosolic Pi to ensure an optimal Pi supply for plants under variable Pi status in the soil.

Web20504 Ensembl ENSG00000124568 ENSMUSG00000021335 UniProt Q14916 Q61983 RefSeq (mRNA) NM_005074 NM_001170638 NM_009198 RefSeq (protein) NP_005065 NP_001164109 NP_033224 Location (UCSC) Chr 6: 25.78 – 25.83 Mb Chr 13: 24.05 – 24.08 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Sodium-dependent … WebJul 25, 2024 · P is a structural component of nucleic acids and phospholipids, and serves various biological functions in energy metabolism, enzyme activation and signal …

WebThe inorganic phosphate transporter (PiT) family is a group of carrier proteins derived from Gram-negative and Gram-positive bacteria, archaea, and eukaryotes. Function [ edit ] …

WebSphingosine-1-phosphate (S1P) lyase (SPL) irreversibly degrades the bioactive sphingolipid S1P and is highly expressed in enterocytes but downregulated in colon cancer. ... SPL promoted tumorigenic transformation through a pathway involving extracellular transport of S1P through S1P transporter spinster homolog 2 (SPNS2), S1P receptor ... css for outlineWebApr 10, 2024 · One such protein, ceramide-1-phosphate transfer protein (CPTP) transports ceramide-1-phosphate (C1P), ... (r LxS, Q) is consistent with CPTP’s observed function as a C1P transporter: CPTP serves as a free energetically favorable vehicle for C1P transport between even more favorable states in which C1P is part of a membrane. earle reed boilermakerWebMay 27, 2024 · PHOSPHATE TRANSPORTER TRAFFIC FACILITATOR1 is a plant-specific SEC12-related protein that enables the endoplasmic reticulum exit of a high-affinity … earle rainwater funeral in summervilleWebJun 5, 2024 · Since the identification of the major renal inorganic phosphate (P i) transporter, encoded by SLC34A1, in 1993, advances in molecular and cell biology and biophysical and microscopy techniques... css for safari only not chromeWebFeb 1, 2024 · Plants absorb Pi mainly from the soil via roots [9, 10], and PHOSPHATE TRANSPORTER 1 (PHT1) family genes play an important role in this process [11, 12]. Thirteen and nine PHT1 genes have been identified in rice and Arabidopsis , respectively [ 13 , 14 ], and most of them are induced by Pi deficiency in roots and participate in Pi … earle raymond hedrickWebOct 1, 2004 · Glycerol-3-phosphate (G3P) plays a major role in glycolysis and phospholipid biosynthesis in the cell. Escherichia coli uses a secondary membrane transporter protein, GlpT, to uptake G3P into the cytoplasm. The crystal structure of the protein was recently determined to 3.3 Å resolution. earles farm horringerWebApr 10, 2024 · One such protein, ceramide-1-phosphate transfer protein (CPTP) transports ceramide-1-phosphate (C1P), ... (r LxS, Q) is consistent with CPTP’s observed function as … css for schleife