Ferroptotic 翻译
WebIn addition, the expression level of HAAO is positively correlated with lipid peroxidation and clinical outcome. Together, the findings demonstrate that tryptophan metabolism works as a new anti-ferroptotic pathway to promote tumour growth, and targeting this pathway will be a promising therapeutic approach for cancer treatment. WebOct 7, 2024 · Core Molecular Mechanisms of Ferroptosis. The central role of lipid peroxidation in driving ferroptotic cell death indicates that ferroptosis can be caused by the collapse of the glutathione (GSH) …
Ferroptotic 翻译
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WebFerroptosis is an iron-dependent form of regulated necrosis. It is implicated in various human diseases, including ischemic organ damage and cancer. Here, we report the crucial role of autophagy, particularly autophagic degradation of cellular iron storage proteins (a process known as ferritinophagy), in ferroptosis. Web每天有数以百万计的用户使用DeepL进行翻译。. 热门: 英语 译中文、 日语 译中文以及 德语 译中文。. 其他语言:. 爱沙尼亚语 、 保加利亚语 、 波兰语 、 丹麦语 、 俄语 、 芬兰语 、 法语 、 荷兰语 、 捷克语 、 拉脱维亚语 、 立陶宛语 、 罗马尼亚语 ...
Web肝细胞癌(hcc)在我国是最常见的肝癌类型,其发生发展是一个复杂的病理过程。铁死亡作为一种新的细胞死亡方式,在治疗hcc方面有巨大的潜在作用。本文介绍了抑癌因子p53在调控铁死亡中的作用机制,简述其在hcc发生、发展中的作用。抑癌因子p53可以通过影响溶质载体家族7成员11、亚精胺/精胺n1 ... WebApr 11, 2024 · 声明:本专栏主要对生命科学领域的一些期刊文章标题进行翻译,所有内容均由本人手工整理翻译。由于本人专业为生物分析相关,其他领域如果出现翻译错误请谅解。1.Neddylation inhibition induces glutamine uptake and metabolism by targeting CRL3SPOP E3 ligase in cancer cells.Neddylation抑制通过靶向CRL3SPOP E3连接酶诱导癌 ...
Webフェロトーシス(ferroptosis)は、鉄に依存し、過酸化脂質の蓄積によって特徴付けられるプログラム細胞死の一種であり、アポトーシスなどの他の制御された細胞死とは遺伝学的にも生化学的にも異なる 。 フェロトーシスは、グルタチオン依存的な抗酸化防御の破綻によって始まり、脂質の過 ...
WebDespite the recent advances in cancer therapy, cancer chemoresistance looms large along with radioresistance, a major challenge in dire need of thorough and minute investigation. Not long ago, cancer cells were reported to have proven refractory to the ferroptotic cell death, a newly discovered form of regulated cell death (RCD), conspicuous enough to …
WebAug 9, 2024 · Understanding how cancer cells resist ferroptosis is a significant problem that impacts ongoing efforts to stimulate ferroptosis as a therapeutic strategy. We reported that prominin2 is induced by ferroptotic stimuli and functions to resist ferroptotic death. Although this finding has significant im … fish protein amountOxytosis/ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides, and is genetically and biochemically distinct from other forms of regulated cell death such as apoptosis. Oxytosis/ferroptosis is initiated by the failure of the glutathione-dependent antioxidant defenses, resulting in unchecked lipid peroxidation and eventual cell death. Lipophilic antioxidants and iron chelators can prevent ferroptotic cell death. … can dish detergent be used to wash a carWebFeb 21, 2024 · In this study, we found that ferroptotic stress can help macrophages suppress intracellular bacteria by reversing the importation of ferrous iron into bacterial vacuoles via ferroportin and thereby inducing in situ ferroptosis-like bacterial death. Methods: A macrophage model of bacterial invasion was established to monitor dynamic … can dish detergent be used to wash clothesWeb刘华元 史光军 [摘要] 铁死亡是一种以细胞内铁依赖的脂质过氧化物蓄积为特征的细胞死亡方式,它与细胞典型的坏死、凋亡和自噬不同,在形态学、生物化学和遗传学上具有独特性。 can dish detergent give yeast infectionsWebMay 27, 2024 · Ferroptotic cell death can often interact with immunity through complicated cellular–molecular mechanisms in multiple ways. Firstly, ferroptotic cells can release danger signals like damage-associated molecular patterns (DAMPs) or metabolites that may serve as messengers to surrounding immune cells []. The released signal can be either ... fish protein analysisWeb铁死亡(ferroptosis), 是一种调节性细胞死亡形式,其特征是铁依赖性脂质过氧化物积累到致死水平。. 这种不同于凋亡、坏死、自噬的新型细胞死亡方式,几乎以一己之力摧枯拉朽般地掀起研究狂潮,至今热度不减。. 今 … fish proteinWebFerroptosis is an iron-dependent, non-apoptotic form of regulated cell death caused by lipid peroxidation, which is controlled by integrated oxidation and antioxidant systems. The iron-containing enzyme lipoxygenase is the main promoter of ferroptosis by producing lipid hydroperoxides, and its function relies on the activation of ACSL4 ... fish protection at water diversions